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KMID : 0374919850060040629
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Inje Medical Journal
1985 Volume.6 No. 4 p.629 ~ p.632
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Malignant Lymphoma of Thyroid Ossociated With Chronic Lymphocytic Thyroiditis
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홍성란/Hong, sung-Ran
윤귀옥/김성숙/조혜제/고일향/김홍용/Yoon, Gui-Ohk/Kim, Seong-Sook/Cho, Hye-Jea/Ko, Ill-Hyang/Kim, Hong-Yong
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Abstract
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Primary lymphomas of the thyroid occur predominantly in elderly women who present with histories of rapid enlargement of the thyroid gland, often with dysphagia, hoarseness, and symtoms of tracheal compression. Involvement of only one lobe is common. Malignant lymphoma of thyroid has been frequently associated with lymphocytic thyroiditis. Recently we experienced a case of thyroid lymphoma associated with an underlying lymphocytic thyroiditis in 64-year-old female who complained of rapidL frowing firm, well circumscribed movable mass, n anterior neck for 3 months. The thyroid function was within normal limits. Grossly, the entire lobe was nearly replaced by homogeneous white yellow rubbery mass of fish flesh glistening apperance. On light.microscopy, it was histologic type of malignant lymphona by the Rappaport classification (high grade, large cell, immunoblastic type by Working formulation; FCC, immunoblastic type by Lukes-Colline classification), associated with chronic lymphocytic thyroiditis. All 14 nodes found in the adjacent tissue are partially or totally replaced by lymphomatous changes.
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